Title : Enhancement of renal and hepatic glutathione metabolism by dimethylthiourea.

Pub. Date : 1993 Feb

PMID : 8430431






2 Functional Relationships(s)
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1 Seven days of daily DMTU therapy significantly (P < 0.001) increased renal and hepatic GSH content by 36 and 54%, respectively, which was associated with a significant (P < 0.001) increase in the renal activities of glutathione peroxidase (GP) by 38%, glutathione transferase (GT) by 92%, and glutathione reductase (GR) by 19% (P < 0.05). 1,3-dimethylthiourea glutathione-disulfide reductase Rattus norvegicus
2 Seven days of daily DMTU therapy significantly (P < 0.001) increased renal and hepatic GSH content by 36 and 54%, respectively, which was associated with a significant (P < 0.001) increase in the renal activities of glutathione peroxidase (GP) by 38%, glutathione transferase (GT) by 92%, and glutathione reductase (GR) by 19% (P < 0.05). 1,3-dimethylthiourea glutathione-disulfide reductase Rattus norvegicus