Title : Interleukin-1 stimulates the aromatase activity of human placental cytotrophoblasts.

Pub. Date : 1993 Feb

PMID : 8425476






2 Functional Relationships(s)
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1 In time-course studies, significant stimulation of the conversion of androstenedione to estrogens by hIL-1 beta could be detected as early as after 4 h of treatment and persisted for at least 24 h. Human IL-1 alpha stimulated the conversion of androstenedione to estrogens to an extent similar to that of hIL-1 beta, whereas the effects of murine IL-1 beta on aromatase activity were inconsistent. Androstenedione interleukin 1 alpha Homo sapiens
2 In time-course studies, significant stimulation of the conversion of androstenedione to estrogens by hIL-1 beta could be detected as early as after 4 h of treatment and persisted for at least 24 h. Human IL-1 alpha stimulated the conversion of androstenedione to estrogens to an extent similar to that of hIL-1 beta, whereas the effects of murine IL-1 beta on aromatase activity were inconsistent. Androstenedione interleukin 1 alpha Homo sapiens