Title : Characterization of specific cytochrome P450 enzymes responsible for the metabolism of diazepam in hepatic microsomes of adult male rats.

Pub. Date : 1993 Jan 7

PMID : 8424823






1 Functional Relationships(s)
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1 CYP2D1 antisera inhibited the aromatic hydroxylation of DZ (98%) and subsequent formation of 4"-hydroxy-DZ (4"HDZ). 4'-hydroxydiazepam cytochrome P450, family 2, subfamily d, polypeptide 1 Rattus norvegicus