Title : The relation between insulin sensitivity and the fatty-acid composition of skeletal-muscle phospholipids.

Pub. Date : 1993 Jan 28

PMID : 8418404






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1 The relation between insulin sensitivity and the fatty-acid composition of skeletal-muscle phospholipids. Phospholipids insulin Homo sapiens
2 Skeletal muscle is a major site of insulin action, and insulin sensitivity may be related to the fatty-acid composition of the phospholipids within the muscle membranes involved in the action of insulin. Phospholipids insulin Homo sapiens
3 Skeletal muscle is a major site of insulin action, and insulin sensitivity may be related to the fatty-acid composition of the phospholipids within the muscle membranes involved in the action of insulin. Phospholipids insulin Homo sapiens
4 METHODS: We determined the relation between the fatty-acid composition of skeletal-muscle phospholipids and insulin sensitivity in two groups of subjects. Phospholipids insulin Homo sapiens
5 CONCLUSIONS: Decreased insulin sensitivity is associated with decreased concentrations of polyunsaturated fatty acids in skeletal-muscle phospholipids, raising the possibility that changes in the fatty-acid composition of muscles modulate the action of insulin. Phospholipids insulin Homo sapiens