Title : AS-183, a novel inhibitor of acyl-CoA: cholesterol acyltransferase produced by Scedosporium sp. SPC-15549.

Pub. Date : 1993 Aug

PMID : 8407580






1 Functional Relationships(s)
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1 AS-183 inhibited ACAT activity in an enzyme assay system using rabbit liver microsomes with an IC50 value of 0.94 microM. 2,4-dimethyl-2-hydroxy-5-(1,3,5,7-tetramethylnonyl)-3(2H)furanone sterol O-acyltransferase 1 Oryctolagus cuniculus