Title : [Effect of lipoprotein on phosphatidylinositol -4,5-bisphosphate and phosphatidic acid in platelet].

Pub. Date : 1993 Feb

PMID : 8391903






4 Functional Relationships(s)
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1 Studies were designed to explore the effects of thrombin, LDL, HDL plus LDL on the changes of the important metabolites: phosphatidylinositol-4,5-bisphosphate (PIP2) and phosphatidic acid (PA) of phosphatidylinositol cycle (PI). Phosphatidylinositol 4,5-Diphosphate coagulation factor II, thrombin Homo sapiens
2 Studies were designed to explore the effects of thrombin, LDL, HDL plus LDL on the changes of the important metabolites: phosphatidylinositol-4,5-bisphosphate (PIP2) and phosphatidic acid (PA) of phosphatidylinositol cycle (PI). Phosphatidylinositol 4,5-Diphosphate coagulation factor II, thrombin Homo sapiens
3 The results indicated that both thrombin and LDL caused a significant decrease of PIP2 within 15 seconds. Phosphatidylinositol 4,5-Diphosphate coagulation factor II, thrombin Homo sapiens
4 The effects of thrombin or LDL on PIP2 decrease and PA increase were also both dose-dependent. Phosphatidylinositol 4,5-Diphosphate coagulation factor II, thrombin Homo sapiens