Title : Selective binding of gelsolin to actin monomers containing ADP.

Pub. Date : 1993 Jul 5

PMID : 8390984






2 Functional Relationships(s)
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Protein Name
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1 Monomeric ATP-actin in 2 mM MgCl2 and 150 mM KCl slowly destroys the filament-severing activity of gelsolin with kinetics that are first order in actin concentration and with an apparent bimolecular rate constant of 0.021 +/- 0.007 microM-1 s-1. Magnesium Chloride gelsolin Homo sapiens
2 Coincident with the slow complex formation in MgCl2, the actin bound to the calcium-sensitive actin binding domain of gelsolin hydrolyzes its ATP to ADP. Magnesium Chloride gelsolin Homo sapiens