Pub. Date : 1993 May 25
PMID : 8390258
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Superoxide is an antagonist of antiinflammatory drugs that inhibit hypochlorous acid production by myeloperoxidase. | Hypochlorous Acid | myeloperoxidase | Homo sapiens |
| 2 | Myeloperoxidase, the most abundant enzyme in neutrophils, catalyses the conversion of hydrogen peroxide and chloride to hypochlorous acid. | Hypochlorous Acid | myeloperoxidase | Homo sapiens |
| 3 | The inhibitory effects of the drugs on hypochlorous acid production, either by cells stimulated with phorbol myristate acetate or by myeloperoxidase and xanthine oxidase, were significantly less than those determined with myeloperoxidase and reagent hydrogen peroxide. | Hypochlorous Acid | myeloperoxidase | Homo sapiens |
| 4 | We also observed that with the xanthine oxidase system, inhibition of hypochlorous acid production by dapsone decreased markedly as the concentration of myeloperoxidase increased. | Hypochlorous Acid | myeloperoxidase | Homo sapiens |