Title : The steroid binding domain influences intracellular solubility of the baculovirus overexpressed glucocorticoid and mineralocorticoid receptors.

Pub. Date : 1993 May 25

PMID : 8388719






3 Functional Relationships(s)
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1 The expression and formation of the oligomeric steroid binding form of the glucocorticoid receptor (GR) and the mineralocorticoid receptor (MR) were further examined in the baculovirus expression system. Steroids nuclear receptor subfamily 3 group C member 1 Homo sapiens
2 The expression and formation of the oligomeric steroid binding form of the glucocorticoid receptor (GR) and the mineralocorticoid receptor (MR) were further examined in the baculovirus expression system. Steroids nuclear receptor subfamily 3 group C member 1 Homo sapiens
3 On the other hand, in vitro incubation of monomeric GR or MR partially purified from the insoluble receptor aggregates with reticulocyte lysate resulted in complete reconstitution of the oligomeric receptor complex with a concomitant restoration of full steroid binding ability. Steroids nuclear receptor subfamily 3 group C member 1 Homo sapiens