Pub. Date : 1993 Sep 15
PMID : 8373423
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Platelet activating factor (PAF) primes vascular actions of mediators such as histamine and stimulates human umbilical vein endothelial cells (HUVECs) to produce prostacyclin (PGI2), which is important for the regulation of vascular tone, perfusion and hemostasis. | Histamine | PCNA clamp associated factor | Homo sapiens |
| 2 | Platelet activating factor (PAF) primes vascular actions of mediators such as histamine and stimulates human umbilical vein endothelial cells (HUVECs) to produce prostacyclin (PGI2), which is important for the regulation of vascular tone, perfusion and hemostasis. | Histamine | PCNA clamp associated factor | Homo sapiens |
| 3 | We demonstrate that pretreatment of HUVECs with PAF enhances thrombin- or histamine-induced rises of cytosolic free Ca(++)-concentration and subsequent Ca(++)-dependent PGI2-synthesis. | Histamine | PCNA clamp associated factor | Homo sapiens |
| 4 | This suggests cooperative effects of PAF on activation processes induced by thrombin or histamine in HUVECs. | Histamine | PCNA clamp associated factor | Homo sapiens |