Title : Osmotically-induced nerve taurine depletion and the compatible osmolyte hypothesis in experimental diabetic neuropathy in the rat.

Pub. Date : 1993 Jul

PMID : 8359577






1 Functional Relationships(s)
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1 Prevention of sorbitol accumulation with the aldose reductase inhibitor sorbinil increased nerve taurine levels by 22% (p < 0.05) when compared with untreated diabetic animals. Sorbitol aldo-keto reductase family 1 member B1 Rattus norvegicus