Pub. Date : 1993 Aug 9
PMID : 8357002
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Expression of PGHS-2 is inhibited by antiinflammatory glucocorticoids, lending further support to the hypothesis that this enzyme produces prostaglandins involved in inflammation. | Prostaglandins | prostaglandin-endoperoxide synthase 2 | Mus musculus |
| 2 | Screening for drugs that preferentially inhibit PGHS-2 may allow identification of NSAIDs that reduce inflammation, but spare renal and gastric prostaglandin synthesis, thus reducing the untoward side effects commonly associated with most NSAIDs. | Prostaglandins | prostaglandin-endoperoxide synthase 2 | Mus musculus |