Title : Association of protein kinase C activation with induction of ornithine decarboxylase in murine but not human keratinocyte cultures.

Pub. Date : 1993

PMID : 8352882






3 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 When MEK and HEK cultures were treated with TPA for 3 h, less than 30% of the control level of PKC activity was detected, indicating that TPA-induced downregulation of PKC was similar in MEKs and HEKs. Tetradecanoylphorbol Acetate mitogen-activated protein kinase kinase 7 Homo sapiens
2 After treatment with TPA, MEK cultures produced a large induction of both c-jun and c-fos mRNA by 60 min, as determined by northern blot analysis, and a large induction of ODC mRNA and enzyme activity by 6 h. TPA treatment of cultured HEKs, however, did not induce ODC activity; in fact, less activity, compared with that of control cultures, was observed. Tetradecanoylphorbol Acetate mitogen-activated protein kinase kinase 7 Homo sapiens
3 After treatment with TPA, MEK cultures produced a large induction of both c-jun and c-fos mRNA by 60 min, as determined by northern blot analysis, and a large induction of ODC mRNA and enzyme activity by 6 h. TPA treatment of cultured HEKs, however, did not induce ODC activity; in fact, less activity, compared with that of control cultures, was observed. Tetradecanoylphorbol Acetate mitogen-activated protein kinase kinase 7 Homo sapiens