Title : Induction of cellular p53 activity by DNA-damaging agents and growth arrest.

Pub. Date : 1993 Jul

PMID : 8321226






1 Functional Relationships(s)
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1 IR, UV radiation, and methylmethane sulfonate were found to induce p53 activity when a stably integrated reporter construct containing functional p53-binding sites was used and also in mobility shift assays with a p53-binding site from the GADD45 gene, and IR-inducible gene previously associated with growth arrest. Methyl Methanesulfonate growth arrest and DNA damage inducible alpha Homo sapiens