Pub. Date : 1993 Dec
PMID : 8300756
9 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Estrogen receptor-negative breast cancer cells transfected with the estrogen receptor exhibit increased RAR alpha gene expression and sensitivity to growth inhibition by retinoic acid. | Tretinoin | estrogen receptor 1 | Homo sapiens |
| 2 | Estrogen receptor-negative breast cancer cells transfected with the estrogen receptor exhibit increased RAR alpha gene expression and sensitivity to growth inhibition by retinoic acid. | Tretinoin | estrogen receptor 1 | Homo sapiens |
| 3 | We and others have shown previously that retinoic acid (RA) selectively inhibits the growth of estrogen receptor (ER)-positive human breast carcinoma (HBC) cells and ER-negative cells are refractory to RA inhibition of growth. | Tretinoin | estrogen receptor 1 | Homo sapiens |
| 4 | We and others have shown previously that retinoic acid (RA) selectively inhibits the growth of estrogen receptor (ER)-positive human breast carcinoma (HBC) cells and ER-negative cells are refractory to RA inhibition of growth. | Tretinoin | estrogen receptor 1 | Homo sapiens |
| 5 | We and others have shown previously that retinoic acid (RA) selectively inhibits the growth of estrogen receptor (ER)-positive human breast carcinoma (HBC) cells and ER-negative cells are refractory to RA inhibition of growth. | Tretinoin | estrogen receptor 1 | Homo sapiens |
| 6 | We and others have shown previously that retinoic acid (RA) selectively inhibits the growth of estrogen receptor (ER)-positive human breast carcinoma (HBC) cells and ER-negative cells are refractory to RA inhibition of growth. | Tretinoin | estrogen receptor 1 | Homo sapiens |
| 7 | The ER-negative cells inherently express lower levels of RAR alpha and retinoic acid response element (RARE)-mediated RA-induced CAT activity. | Tretinoin | estrogen receptor 1 | Homo sapiens |
| 8 | The ER-negative cells inherently express lower levels of RAR alpha and retinoic acid response element (RARE)-mediated RA-induced CAT activity. | Tretinoin | estrogen receptor 1 | Homo sapiens |
| 9 | In this study we report that when ER-negative MDA-MB-231 cells were transfected with the ER gene they not only expressed higher levels of RAR alpha and RARE-mediated RA-induced CAT gene expression, but their growth was not inhibited by RA. | Tretinoin | estrogen receptor 1 | Homo sapiens |