Title : Mode of binding of folate analogs to thymidylate synthase. Evidence for two asymmetric but interactive substrate binding sites.

Pub. Date : 1994 Jan 21

PMID : 8294436






1 Functional Relationships(s)
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Protein Name
Organism
1 Thymidylate synthase bound both mono and polyglutamylated folate substrates and analogs more tightly in the presence of deoxyuridylate. 2'-deoxyuridylic acid thymidylate synthetase Homo sapiens