Title : Anisomycin and rapamycin define an area upstream of p70/85S6k containing a bifurcation to histone H3-HMG-like protein phosphorylation and c-fos-c-jun induction.

Pub. Date : 1994 Feb

PMID : 8289787






1 Functional Relationships(s)
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1 Anisomycin, a translational inhibitor, synergizes with growth factors and phorbol esters to superinduce c-fos and c-jun by a number mechanisms, one of which is its ability to act as a potent signalling agonist, producing strong, prolonged activation of the same nuclear responses as epidermal growth factor or tetradecanoyl phorbol acetate. Phorbol Esters Fos proto-oncogene, AP-1 transcription factor subunit Homo sapiens