Title : Neural regulation of peptide YY secretion.

Pub. Date : 1993 Nov 3

PMID : 8278624






5 Functional Relationships(s)
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1 Atropine, hexamethonium and atropine plus hexamethonium treatment blocked food-induced release of PYY significantly. Atropine peptide YY Canis lupus familiaris
2 Atropine, hexamethonium and atropine plus hexamethonium treatment blocked food-induced release of PYY significantly. Atropine peptide YY Canis lupus familiaris
3 Integrated release of PYY in response to food alone and in combination with atropine, hexamethonium and atropine plus hexamethonium were 8.8 +/- 2.2, -1.1 +/- 2.3, -2.7 +/- 2.2 and -3.2 +/- 3.1 (ng (0-150) min/ml), respectively. Atropine peptide YY Canis lupus familiaris
4 Integrated release of PYY in response to food alone and in combination with atropine, hexamethonium and atropine plus hexamethonium were 8.8 +/- 2.2, -1.1 +/- 2.3, -2.7 +/- 2.2 and -3.2 +/- 3.1 (ng (0-150) min/ml), respectively. Atropine peptide YY Canis lupus familiaris
5 Together, these data suggest that food-stimulated PYY secretion is dependent on ganglionic transmission and an atropine-blockable postganglionic parasympathetic pathway; and that PYY release is inhibited tonically, probably through a vagal cholinergic mechanism. Atropine peptide YY Canis lupus familiaris