Title : Role of interchain disulfide bonds on the assembly and secretion of human fibrinogen.

Pub. Date : 1994 Jan 7

PMID : 8276866






1 Functional Relationships(s)
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1 The cysteines involved in joining the 2 half-molecules of fibrinogen and also those located on either side of the alpha-helical coiled-coil region, were substituted, by site-directed mutagenesis, with serine. Serine fibrinogen beta chain Homo sapiens