Title : Interleukin 1 alpha stimulates nuclear phospholipase C in human osteosarcoma SaOS-2 cells.

Pub. Date : 1994 Jan 7

PMID : 8276785






1 Functional Relationships(s)
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1 While confirming the existence of an autonomous nuclear phosphoinositide signaling system, our data clearly indicate that in SaOS-2 cells one of the earliest events following IL-1 alpha treatment is the breakdown of nuclear phosphatidylinositol monophosphate and phosphatidylinositol bisphosphate because of the activation of a specific nuclear PLC isoform. Phosphatidylinositols interleukin 1 alpha Homo sapiens