Title : Apparent antioxidant effect of l-deprenyl on hydroxyl radical formation and nigral injury elicited by MPP+ in vivo.

Pub. Date : 1993 Oct 26

PMID : 8276076






1 Functional Relationships(s)
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1 Using a modified microdialysis procedure, we confirmed that intrastriatal administration of 1-methyl-4-phenylpyridinium ion (MPP+) induced a sustained overflow of dopamine accompanied by increased formation of hydroxyl free radicals (.OH) as reflected by salicylate hydroxylation. 1-Methyl-4-phenylpyridinium M-phase phosphoprotein 6 Homo sapiens