Title : Acute haemodynamic effects and pharmacokinetics of ramipril in patients with heart failure. A placebo controlled three-dose study.

Pub. Date : 1993

PMID : 8276048






2 Functional Relationships(s)
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1 The aim of the present study was primarily to evaluate the haemodynamic effects of the ACE-inhibitor ramipril which is active via its metabolite ramiprilat. ramiprilat angiotensin I converting enzyme Homo sapiens
2 Complete inhibition of ACE-activity was seen at a mean plasma concentration of ramiprilat of 4.7 ng.ml-1. ramiprilat angiotensin I converting enzyme Homo sapiens