Pub. Date : 1993 Sep
PMID : 8271212
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | To this end we investigated the effects of frusemide and bumetanide, two different inhibitors of the macula densa Na(+)-K(+)-2Cl- cotransport, on pressure-dependent renin release from isolated perfused rat kidneys. | Furosemide | renin | Rattus norvegicus |
| 2 | The vasorelaxant effects of frusemide and bumetanide were paralleled by an increase of renin secretion to a maximum of 21 +/- 4 (ng Ang I h-1) min-1 g-1 (n = 10). | Furosemide | renin | Rattus norvegicus |
| 3 | On a molar basis bumetanide was twice as potent as frusemide in stimulating renin secretion. | Furosemide | renin | Rattus norvegicus |