Title : Coupling of recombinant 5-lipoxygenase and leukotriene A4 hydrolase activities and transcellular metabolism of leukotriene A4 in Sf9 insect cells.

Pub. Date : 1993 Dec 1

PMID : 8269937






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 When Sf9 cells expressing 5-lipoxygenase are incubated in the presence of A23187 and arachidonic acid, (5S)-hydroperoxy-6-trans-8,11,14-cis-eicosatetraenoic acid 5-H(P)ETE and LTA4 are synthesized in a ratio of 5:1 for 5-H(P)ETE/LT. Leukotriene A4 arachidonate 5-lipoxygenase Homo sapiens