Title : Involvement of transforming growth factor-alpha and its receptor in the growth response of cultured human epidermal cells to retinoic acid.

Pub. Date : 1993 Oct

PMID : 8269032






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 The stimulatory effect of RA was inhibited by a blocking monoclonal antibody directed against the binding domain of the EGF receptor. Tretinoin epidermal growth factor Homo sapiens
2 Decreased TGF alpha binding capacity is thought to be due to the ability of RA to stimulate TGF alpha, thereby resulting in EGF receptor binding and internalization. Tretinoin epidermal growth factor Homo sapiens