Title : c-fos induction by stress can be mediated by the SRE.

Pub. Date : 1993 Dec 15

PMID : 8267588






3 Functional Relationships(s)
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1 Stressors, including heat shock, arsenite and cadmium can induce c-fos transcription, but a heat shock element in the c-fos promoter has not been described. arsenite Fos proto-oncogene, AP-1 transcription factor subunit Homo sapiens
2 In this report we show that the induction of c-fos by heat shock, arsenite and cadmium can be mediated by the serum response element. arsenite Fos proto-oncogene, AP-1 transcription factor subunit Homo sapiens
3 Furthermore we show that casein kinase II, which has been proposed to be involved in serum induction via the serum response element, may also be involved in heat shock, arsenite and cadmium induction of c-fos. arsenite Fos proto-oncogene, AP-1 transcription factor subunit Homo sapiens