Title : Rieger syndrome revisited: experimental approaches using pharmacologic and antisense strategies to abrogate EGF and TGF-alpha functions resulting in dysmorphogenesis during embryonic mouse craniofacial morphogenesis.

Pub. Date : 1993 Oct 1

PMID : 8266997






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Tyrphostin RG 50864, which inhibits EGF receptor kinase activity, inhibits EGF or TGF-alpha stimulation of tyrosine phosphorylation in a concentration-dependent manner and severely retards mandibular development [Shum et al., 1993: Development 118:903-917]. Tyrphostins epidermal growth factor receptor Mus musculus