Title : Human cytochrome P450 3A4: enzymatic properties of a purified recombinant fusion protein containing NADPH-P450 reductase.

Pub. Date : 1993 Dec 15

PMID : 8265621






1 Functional Relationships(s)
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1 Human cytochrome P450 3A4 is recognized as the catalyst for the oxygen-dependent metabolism of a diverse group of medically important chemicals, including the immunosuppressive agent cyclosporin; macrolide antibiotics, such as erythromycin; drugs such as benzphetamine, nifedipine, and cocaine; and steroids; such as cortisol and testosterone to name but a few. Cyclosporine cytochrome P450 family 3 subfamily A member 4 Homo sapiens