Pub. Date : 1993
PMID : 8261576
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | At a concentration of 2.5 mM, nicotinamide (NA), an inhibitor of poly(ADP-ribose) polymerase (PARP), significantly potentiated the cytotoxicity of cisplatin (DDP) in a DDP-resistant rat ovarian tumor cell line (O-342/DDP) in vitro, whereas the same treatment had no substantial effect on DDP"s cytotoxic activity against the DDP-sensitive parental line (O-342). | Niacinamide | poly (ADP-ribose) polymerase 1 | Rattus norvegicus |
| 2 | At a concentration of 2.5 mM, nicotinamide (NA), an inhibitor of poly(ADP-ribose) polymerase (PARP), significantly potentiated the cytotoxicity of cisplatin (DDP) in a DDP-resistant rat ovarian tumor cell line (O-342/DDP) in vitro, whereas the same treatment had no substantial effect on DDP"s cytotoxic activity against the DDP-sensitive parental line (O-342). | Niacinamide | poly (ADP-ribose) polymerase 1 | Rattus norvegicus |