Title : CYP1A2-catalyzed conversion of dietary heterocyclic amines to their proximate carcinogens is their major route of metabolism in humans.

Pub. Date : 1994 Jan 1

PMID : 8261468






1 Functional Relationships(s)
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1 The inhibitory potential of furafylline in vivo was first assessed by determining its effect on clearance of phenacetin to paracetamol by the model CYP1A2-dependent O-deethylation pathway. Phenacetin cytochrome P450 family 1 subfamily A member 2 Homo sapiens