Title : The platelet-stimulating effect of adrenaline through alpha 2-adrenergic receptors requires simultaneous activation by a true stimulatory platelet agonist. Evidence that adrenaline per se does not induce human platelet activation in vitro.

Pub. Date : 1993 Sep 1

PMID : 8259557






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 (3) The response of CP/CPK-treated thrombin- or platelet-activating factor (PAF)-stimulated platelets was markedly increased by a subsequent addition of adrenaline. Epinephrine coagulation factor II, thrombin Homo sapiens
2 When hirudin or BN 50726 was added just prior to adrenaline to terminate the activation by thrombin or PAF, respectively, the stimulating effect of adrenaline was also abolished. Epinephrine coagulation factor II, thrombin Homo sapiens