Title : Direct observation and elucidation of the structures of aged and nonaged phosphorylated cholinesterases by 31P NMR spectroscopy.

Pub. Date : 1993 Dec 14

PMID : 8257680






1 Functional Relationships(s)
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1 The broadening of the 31P NMR signal of native OP-ChEs relative to that of OP-Cht is in agreement with the crystal structure of AChE, showing that the active site region of ChEs in solution resides in a deep, narrow gorge. ET bromodomain inhibitor acetylcholinesterase (Cartwright blood group) Homo sapiens