Title : Restoration by bromocriptine of glucocorticoid receptors and glucocorticoid negative feedback on prolactin secretion in estrogen-induced pituitary tumors.

Pub. Date : 1993 Sep

PMID : 8255389






2 Functional Relationships(s)
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1 Presently, we found that bromocriptine (BROM) treatment increased the levels of GCR in DES-T, demonstrated by steroid binding assays and immunocytochemistry using a monoclonal antibody against the type II GCR. Steroids nuclear receptor subfamily 3, group C, member 1 Rattus norvegicus
2 In this respect, inefficient steroid negative feedback on PRL synthesis due to down-regulation of GCR may contribute to hyperprolactinemia. Steroids nuclear receptor subfamily 3, group C, member 1 Rattus norvegicus