Title : Influence of chloroquine or acid treatment of human platelets on the antigenicity of HLA and the 'thrombocyte-specific' glycoproteins Ia/IIa, IIb, and IIb/IIIa.

Pub. Date : 1993

PMID : 8249366






1 Functional Relationships(s)
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1 After treatment with citric acid at pH 3 and chloroquine, the expression of HLA class I was significantly reduced, while the density of the molecules GPIa/IIa, GPIIb, and GPIIb/IIIa (GP = glycoprotein) carrying "thrombocyte-specific" antigens was not or only weakly decreased on the surface of the platelets. Citric Acid multimerin 1 Homo sapiens