Title : Consequences of weak interaction of rho GDI with the GTP-bound forms of rho p21 and rac p21.

Pub. Date : 1993 Nov 15

PMID : 8226937






7 Functional Relationships(s)
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1 Consequences of weak interaction of rho GDI with the GTP-bound forms of rho p21 and rac p21. Guanosine Triphosphate H3 histone pseudogene 16 Homo sapiens
2 Consequences of weak interaction of rho GDI with the GTP-bound forms of rho p21 and rac p21. Guanosine Triphosphate H3 histone pseudogene 16 Homo sapiens
3 Recently, rho GDI has been reported to interact with the GTP-bound form of G25K and rac1 p21 and to inhibit their basal and GTPase-activating protein (GAP)-stimulated GTPase activity. Guanosine Triphosphate H3 histone pseudogene 16 Homo sapiens
4 Here, we examined whether rho GDI interacts with the GTP-bound form of rho p21 and rac p21 and inhibits their basal and rho GAP-stimulated GTPase activity, rho GDI interacted with both the GDP- and GTP-bound forms of rhoA p21 and rac1 p21 as estimated by measuring its ability to form a complex with both forms and to inhibit the membrane-binding activity of both forms. Guanosine Triphosphate H3 histone pseudogene 16 Homo sapiens
5 Here, we examined whether rho GDI interacts with the GTP-bound form of rho p21 and rac p21 and inhibits their basal and rho GAP-stimulated GTPase activity, rho GDI interacted with both the GDP- and GTP-bound forms of rhoA p21 and rac1 p21 as estimated by measuring its ability to form a complex with both forms and to inhibit the membrane-binding activity of both forms. Guanosine Triphosphate H3 histone pseudogene 16 Homo sapiens
6 Here, we examined whether rho GDI interacts with the GTP-bound form of rho p21 and rac p21 and inhibits their basal and rho GAP-stimulated GTPase activity, rho GDI interacted with both the GDP- and GTP-bound forms of rhoA p21 and rac1 p21 as estimated by measuring its ability to form a complex with both forms and to inhibit the membrane-binding activity of both forms. Guanosine Triphosphate H3 histone pseudogene 16 Homo sapiens
7 Here, we examined whether rho GDI interacts with the GTP-bound form of rho p21 and rac p21 and inhibits their basal and rho GAP-stimulated GTPase activity, rho GDI interacted with both the GDP- and GTP-bound forms of rhoA p21 and rac1 p21 as estimated by measuring its ability to form a complex with both forms and to inhibit the membrane-binding activity of both forms. Guanosine Triphosphate H3 histone pseudogene 16 Homo sapiens