Pub. Date : 1993 Nov 15
PMID : 8226909
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Prenylation of Rab5 is dependent on guanine nucleotide binding. | Guanine Nucleotides | RAB5A, member RAS oncogene family | Homo sapiens |
| 2 | Since the latter mutation results in defective GTPase activity, these combined observations indicate that guanine nucleotide binding plays an important role in the geranylgeranylation reaction and suggest that the GDP-bound form of Rab5 is the preferred conformation for interaction with Rab prenyltransferase. | Guanine Nucleotides | RAB5A, member RAS oncogene family | Homo sapiens |