Title : Transcriptional regulation of interleukin-2 gene expression by CD69-generated signals.

Pub. Date : 1993 Nov

PMID : 8223876






1 Functional Relationships(s)
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1 The region extending from -317 to +47 relative to the initiation site of IL-2 gene transcription was shown to contain sequences able to respond to CD69 cross-linking, by enhancing by about 100% a phorbol 12-myristate 13-acetate (PMA)-plus-ionomycin stimulation of CAT activity. Ionomycin interleukin 2 Homo sapiens