Title : Metabolism of benzo(a)pyrene and benzo (a)pyrene derivatives to mutagenic products by highly purified hepatic microsomal enzymes.

Pub. Date : 1976 Aug 25

PMID : 821945






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 The number of mutations induced per nmol of hemoprotein is approximately 3- to 4-fold higher when trans-7,8-dihydroxy-7,8-dihydrobenzo (a)pyrene replaces benzo (a)pyrene as a substrate for the cytochrome P-448-dependent monooxygenase system. Benzo(a)pyrene cytochrome P450, family 1, subfamily a, polypeptide 2 Rattus norvegicus