Title : The Ca(2+)-induced conformational change of gelsolin is located in the carboxyl-terminal half of the molecule.

Pub. Date : 1993 Aug

PMID : 8218904






1 Functional Relationships(s)
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1 Since gelsolin has binding sites in both domains, and the isolated amino terminus binds and severs actin in a calcium-independent manner, our results suggests that the structural transition in the carboxyl-terminal part of intact gelsolin also affects the actin binding properties of the amino-terminal half. Calcium gelsolin Homo sapiens