Title : Prevention and treatment of ocular inflammation with a new class of non-steroidal anti-inflammatory agents.

Pub. Date : 1994 Spring

PMID : 8207338






3 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 Endotoxin induced inflammation indirectly through the release of IL-1 which was inhibited by fewer agents, including CK-17, CK-102 and prednisolone. Prednisolone interleukin 1 alpha Homo sapiens
2 However, the direct effect of IL-1 can only be suppressed by CK-17 and prednisolone. Prednisolone interleukin 1 alpha Homo sapiens
3 Most importantly, CK-17 was found to be 2-fold more potent than prednisolone in inhibiting IL-1-induced uveitis, while no side effects were noted at doses tested to date. Prednisolone interleukin 1 alpha Homo sapiens