Pub. Date : 1994 May
PMID : 8203522
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | In many cell types, the regulation of intracellular pH (pHi) is different in the presence vs. absence of HCO3-. | Bicarbonates | glucose-6-phosphate isomerase | Oryctolagus cuniculus |
| 2 | In Cl(-)-depleted parietal cells, the dependence of maximal proton efflux rate on pHi showed a strong inverse correlation but was identical in the presence and absence of HCO3-. | Bicarbonates | glucose-6-phosphate isomerase | Oryctolagus cuniculus |
| 3 | In Cl(-)-containing cells, there was also some Na(+)-independent, extracellular HCO(3-)- and intracellular Cl(-)-dependent, DIDS-inhibitable pHi recovery from an acid load, most likely due to intracellular Cl(-)-extracellular HCO3- exchange. | Bicarbonates | glucose-6-phosphate isomerase | Oryctolagus cuniculus |
| 4 | Recovery from an alkaline load was primarily mediated by anion exchange, and the dependence of maximal anion exchange rates on pHi was very different in the absence and presence of HCO3-. | Bicarbonates | glucose-6-phosphate isomerase | Oryctolagus cuniculus |
| 5 | In the presence of HCO3-, however, there was an S-shaped dependence of maximal flux rates on pHi, with a steep increase in flux rates between 6.8 and 7.5. | Bicarbonates | glucose-6-phosphate isomerase | Oryctolagus cuniculus |