Title : Targeted mutation of the CREB gene: compensation within the CREB/ATF family of transcription factors.

Pub. Date : 1994 Jun 7

PMID : 8202542






4 Functional Relationships(s)
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1 These data demonstrate that CREB is not the sole mediator of cAMP-dependent transcriptional regulation and probably acts in concert with a specific subset of cAMP response element-binding proteins to transduce the cAMP signal and, in its absence, these same proteins can compensate for CREB function in vivo. Cyclic AMP cAMP responsive element binding protein 1 Mus musculus
2 These data demonstrate that CREB is not the sole mediator of cAMP-dependent transcriptional regulation and probably acts in concert with a specific subset of cAMP response element-binding proteins to transduce the cAMP signal and, in its absence, these same proteins can compensate for CREB function in vivo. Cyclic AMP cAMP responsive element binding protein 1 Mus musculus
3 These data demonstrate that CREB is not the sole mediator of cAMP-dependent transcriptional regulation and probably acts in concert with a specific subset of cAMP response element-binding proteins to transduce the cAMP signal and, in its absence, these same proteins can compensate for CREB function in vivo. Cyclic AMP cAMP responsive element binding protein 1 Mus musculus
4 These data demonstrate that CREB is not the sole mediator of cAMP-dependent transcriptional regulation and probably acts in concert with a specific subset of cAMP response element-binding proteins to transduce the cAMP signal and, in its absence, these same proteins can compensate for CREB function in vivo. Cyclic AMP cAMP responsive element binding protein 1 Mus musculus