Title : Protein kinase C, an inhibitor of oxytocin-stimulated phasic myometrial contractions.

Pub. Date : 1994 Apr

PMID : 8199266






4 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 One of the roles previously reported for protein kinase C (PKC) is modulation of the activity of the phosphatidylinositol signaling pathway. Phosphatidylinositols protein kinase C, gamma Rattus norvegicus
2 One of the roles previously reported for protein kinase C (PKC) is modulation of the activity of the phosphatidylinositol signaling pathway. Phosphatidylinositols protein kinase C, gamma Rattus norvegicus
3 Studies were performed to test the hypothesis that activation of PKC results in inhibition of agonist-stimulated phasic myometrial contractions: contractions that appear to be mediated by phosphatidylinositol signaling mechanisms comparable to those producing cytosolic calcium oscillations. Phosphatidylinositols protein kinase C, gamma Rattus norvegicus
4 These studies have provided support for a role for PKC as an intracellular regulator of the phosphatidylinositol signaling pathway, which itself appears to be part of the myometrial calcium oscillator that results in agonist-stimulated phasic myometrial contractions. Phosphatidylinositols protein kinase C, gamma Rattus norvegicus