Pub. Date : 1994 Jan 12
PMID : 8190118
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | The role of the primary amino groups of lysine sidechains in Ca2+ binding to calreticulin was evaluated by chemical modification of the amino group with 2,4,6-trinitrobenzenesulfonic acid (TNBS). | Lysine | calreticulin | Homo sapiens |
2 | In the C-domain of calreticulin, which contains the low affinity/high capacity Ca2+ binding sites, acidic residues are interspersed at regular intervals with one or more positively charged lysine and arginine residues. | Lysine | calreticulin | Homo sapiens |
3 | Our results indicate that the aminogroups of the lysine sidechains in the C-domain of calreticulin have a role in the low affinity/high capacity Ca2+ binding that is characteristic of this region of the protein and which is proposed to contribute significantly to the capacity of the endoplasmic reticulum Ca2+ store. | Lysine | calreticulin | Homo sapiens |