Title : Presynaptic and postsynaptic effects of neuropeptide Y in the rat pineal gland.

Pub. Date : 1994 Jun

PMID : 8189249






3 Functional Relationships(s)
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Protein Name
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1 Neuropeptide Y is colocalized with noradrenaline in sympathetic fibers innervating the rat pineal gland. Norepinephrine neuropeptide Y Rattus norvegicus
2 At the presynaptic level, neuropeptide Y inhibits by 45%, with an EC50 of 50 nM, the potassium-evoked noradrenaline release from pineal nerve endings. Norepinephrine neuropeptide Y Rattus norvegicus
3 This neuropeptide Y inhibition occurs via the activation of pertussis toxin-sensitive G protein-coupled neuropeptide Y-Y2 receptors and is independent from, but additive to, the alpha 2-adrenergic inhibition of noradrenaline release. Norepinephrine neuropeptide Y Rattus norvegicus