Pub. Date : 1994 Apr
PMID : 8183246
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Kinetics of inhibition by tyrphostins of the tyrosine kinase activity of the epidermal growth factor receptor and analysis by a new computer program. | Tyrphostins | epidermal growth factor receptor | Homo sapiens |
| 2 | The kinetics of inhibition of the epidermal growth factor (EGF) receptor (EGFR) tyrosine kinase (TK) activity by erbstatin, tyrphostins, and lavendustin derivatives were studied in a system that employs poly(Glu6Ala3Tyr) (GAT) and ATP as substrates, after preactivation with EGF. | Tyrphostins | epidermal growth factor receptor | Homo sapiens |
| 3 | Various possible modes of binding at the EGFR-TK active center for the tyrphostins studied are proposed and the significance of the present findings, as well as the interpretations of computer analyses of kinetic data, is discussed. | Tyrphostins | epidermal growth factor receptor | Homo sapiens |