Title : Accumulation of inositol phosphates in low-passage human meningioma cells following treatment with epidermal growth factor.

Pub. Date : 1994 May

PMID : 8169630






2 Functional Relationships(s)
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1 Kinetic analysis of EGF-stimulated inositol phospholipid hydrolysis showed that a sharp and transient increase in IP3 from 5 to 12 minutes post-EGF and a transient but more gradual increase in IP2 from 2 to 12 minutes post-EGF were followed by a gradual and steady increase in IP1, which was significantly greater than control after 5 minutes. Phosphatidylinositols epidermal growth factor Homo sapiens
2 The results suggest a close involvement of inositol phospholipid turnover in human meningioma cells in response to mitogenic stimulation by EGF. Phosphatidylinositols epidermal growth factor Homo sapiens