Pub. Date : 1994 Apr 1
PMID : 8166641
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | AngII treatment of intact cells also activated a cPLA2, as measured in cell-free extracts by the release of radiolabelled arachidonic acid from exogenously added 1-stearoyl-2-[1-14C]arachidonoyl phosphatidylcholine. | Arachidonic Acid | angiotensinogen | Homo sapiens |
| 2 | Together, these results suggest strongly that (1) AngII phosphorylates and activates cPLA2 in a PKC-dependent manner, and that (2) cPLA2 mediates the AngII-induced [3H]arachidonic acid release in vascular smooth-muscle cells. | Arachidonic Acid | angiotensinogen | Homo sapiens |
| 3 | Together, these results suggest strongly that (1) AngII phosphorylates and activates cPLA2 in a PKC-dependent manner, and that (2) cPLA2 mediates the AngII-induced [3H]arachidonic acid release in vascular smooth-muscle cells. | Arachidonic Acid | angiotensinogen | Homo sapiens |