Pub. Date : 1994 Apr 22
PMID : 8163493
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | The rate of 125I-labeled IGF-1 internalization by transfectants overexpressing the wild type IGF-1 receptor was rapid but decreased markedly in the presence of increasing unlabeled IGF-1 (ED50 = 44,000 receptors/cell). | Iodine-125 | insulin like growth factor 1 | Homo sapiens |
2 | The rate of 125I-labeled IGF-1 internalization by transfectants overexpressing the wild type IGF-1 receptor was rapid but decreased markedly in the presence of increasing unlabeled IGF-1 (ED50 = 44,000 receptors/cell). | Iodine-125 | insulin like growth factor 1 | Homo sapiens |
3 | The rate of 125I-labeled IGF-1 internalization by transfectants overexpressing the wild type IGF-1 receptor was rapid but decreased markedly in the presence of increasing unlabeled IGF-1 (ED50 = 44,000 receptors/cell). | Iodine-125 | insulin like growth factor 1 | Homo sapiens |
4 | In contrast, 125I-labeled IGF-1 endocytosis by the mutant kinase-deficient 952STOP cells was slow and not further retarded by unlabeled IGF-1. | Iodine-125 | insulin like growth factor 1 | Homo sapiens |