Title : Characterization of the enzyme responsible for the metabolism of sumatriptan in human liver.

Pub. Date : 1994 Mar 29

PMID : 8161354






1 Functional Relationships(s)
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1 Incubation with clorgyline and deprenyl, probe inhibitors of MAO-A and MAO-B, respectively, showed that [14C]sumatriptan was metabolized by MAO-A; there was no evidence of P450 involvement in its metabolism. Carbon-14 monoamine oxidase A Homo sapiens